THE ALPRAZOLAM DIARIES

Metabolism Alprazolam is thoroughly metabolized in human beings, mostly by cytochrome P450 3A4 (CYP3A4), to 2 major Lively metabolites inside the plasma: 4-hydroxyalprazolam and α-hydroxyalprazolam. The plasma circulation levels of the two active metabolites are fewer than 4% from the parent. The described relative potencies in benzodiazepine rece